Current position
2022 Postdoc at the Department of Chemistry & Molecular Biology, University of Gothenburg, Sweden
Previous positions
2020-2021 Researcher at the Enamine Ltd., Kyiv, Ukraine
2019 Visiting researcher at the Friedrich Schiller University Jena, Germany
2016-2018 Postdoctoral scientist at the Department of Nanobiophotonics, Max Planck Institute for Biophysical Chemistry, Germany
Education
2016 PhD (Biophysics) at the University of Strasbourg, France
2010 MSc, BSc (Organic Chemistry) at the Kyiv National University, Ukraine
contacts: ievgen.shulov@gmail.com
Research
Ievgen Shulov graduated from the Organic Chemistry Chair of Faculty of Chemistry at Kyiv National University named after Taras Shevchenko in 2010. In 2016, he defended his dissertation on the development of new ultrabright fluorescent organic nanoparticles for biological applications under the supervision of Dr. Andrey Klymchenko. Then, he joined the research group of Prof. Dr. Stefan W. Hell, where he was working on the synthesis of dye-ligand conjugates under the direction of Dr. Vladimir N. Belov. These new fluorescent bioconjugates were further applied for the labeling and imaging of cellular ultrastructures with unprecedented resolution below the diffraction limit of light, which was possible to achieve by using STED nanoscopy.
In August 2020, he joined Enamine company, one of the leading providers of drug-discovery services, where he was assigned to develop new assays for screening large compound libraries. At the beginning of 2022, Ievgen started to work in Nhu Phan’s research group as a postdoctoral fellow. He is currently involved in the projects to develop novel fluorescent markers for correlative microscopy, which combines NanoSIMS with super-resolution fluorescence microscopy, particularly STED nanoscopy. These novel fluorescent markers are intended to be applied further for studying neurodegenerative diseases in the human brain.
Publications
Ultrafast photophysics of the environment-sensitive 4′-methoxy-3-hydroxyflavone fluorescent dye. Skilitsi AI, Agathangelou D, Shulov I, Conyard J, Haacke S, Mély Y,
Klymchenko A, Léonard J. Phys Chem Chem Phys. 2018 Mar 14; 20(11):7885-7895. doi:
10.1039/c7cp08584b. PMID: 29509200
Protein-Sized Bright Fluorogenic Nanoparticles Based on Cross-Linked Calixarene Micelles with Cyanine Corona. Shulov I, Rodik RV, Arntz Y, Reisch A, Kalchenko VI, Klymchenko AS. Angew Chem Int Ed Engl. 2016 Dec 19; 55(51):15884-15888. doi:
10.1002/anie.201609138. PMID: 27862803
Non-coordinating anions assemble cyanine amphiphiles into ultra-small fluorescent nanoparticles. Shulov I, Arntz Y, Mély Y, Pivovarenko VG, Klymchenko AS. Chem Commun (Camb). 2016 Jun 28; 52(51):7962-5. doi: 10.1039/c6cc03716j. PMID: 27251475
Fluorinated counterion-enhanced emission of rhodamine aggregates:
ultrabright nanoparticles for bioimaging and light-harvesting. Shulov I, Oncul S, Reisch A, Arntz Y, Collot M, Mely Y, Klymchenko AS. Nanoscale. 2015 Nov 21; 7(43):18198-210. doi: 10.1039/c5nr04955e. PMID: 26482443
Squaraine as a bright, stable and environment-sensitive far-red label for receptor-specific cellular imaging. Karpenko IA, Klymchenko AS, Gioria S, Kreder R, Shulov I, Villa P,
Mély Y, Hibert M, Bonnet D. Chem Commun (Camb). 2015 Feb 18;51(14):2960-3. doi:
10.1039/c4cc09113b. PMID: 25594279
Tuning the color and photostability of perylene diimides inside polymer nanoparticles: towards biodegradable substitutes of quantum dots. Trofymchuk K, Reisch A, Shulov I, Mély Y, Klymchenko AS. Nanoscale. 2014 Nov 7;6(21):12934-42. doi: 10.1039/c4nr03718a. PMID: 25233438
Highly lipophilic fluorescent dyes in nano-emulsions: towards bright non-leaking nano-droplets. Klymchenko AS, Roger E, Anton N, Anton H, Shulov I, Vermot J, Mely Y,
Vandamme TF. RSC Adv. 2012 Oct 29;2(31):11876-11886. doi: 10.1039/C2RA21544F. PMID: 29242742